The use of PRF in Periodontitis

♦ What is periodontitis ?

Periodontitis is the irreversible loss of attachment to the connective tissue supporting the alveolar bone. It is an inflammatory desease characterized by the distruction of alveolar bone, root cement, periodontal ligament as a response to elicited by microbial accumulance on tooth surface. (1)

♦ Periodontal desease

Periodontitis is the main cause of tooth losing .The aim of periodontal therapy , is to eliminate the inflammatory process, to stop the progression of periodontal desease and to regenerate the lost periodontal tissues. (2)                                                                                                                                    Earlier attemps to archive regeneration , included denator of the interdental bone to treat intrabony defect and the use of autografts to fill the surgical site. Good results have been taken in treatment of periodontitis using a combination of graft material and collagen membrane (3).

But recently , the focus is in the use of ‘growth factors’.The periodontal wound healing , needs the colaburation of epithelial cells , gingival fibroblasts , periodontal ligament cells and osteoblasts.                                                             There is evidence that the presence of growth factors , cytokinins in platelets , play an important role in the wound healing.Platelets also secrete fibrin , fibronectin and vitronectin which are a matrix for the connective tissue .These leads to the use of platelets in periodontal desease (4)

♦ Role of platelets in periodontal wound healing

Platelets play a key role in wound healing and hence wound healing after periodontal treatment can be accelerated by the use of platelet concentrates.The wound healing process